Development of a defined culture medium for human pluripotent stem cells
- bioreactor with murine embryonic stem cells; coloured using a pluripotency marker SSEA-1 (red)
Human embryonic stem cells are used for basic research and for clinical application. Their ability to differentiate into each cell of the three germ layers (endoderm, ectoderm and mesoderm), in contrast to adult stem cells, makes them very attractive for the generation of cell and tissue replacement.
This project is being funded within the framework of the German “Central Innovation Program for SMEs” (ZIM, “Zentrales Innovationsprogramm Mittelstand”) as a cooperation project between companies and research institutions. Project sponsor is AiF e.V., the German Federation of Industrial Research Associations. Cooperation partner is the study group Experimental Chemistry, Bioreactor Group, head: Prof Dr Zeilinger, Charité, Berlin-Brandenburg Center for Regenerative Therapies (BCRT).
Development and optimisation of serum replacement solutions for mesenchymal stem cells
- mesenchymal stem cells
Multipotent mesenchymal stem cells (MSC) can be differentiated in vitro into different mesenchymal tissues (bone, cartilage and adipose tissue), which makes them a potential source for biological tissue engineering of mesenchymal tissue.
The project is being funded within the scope of the German “Central innovation program for SMEs” (ZIM, “Zentrales Innovationsprogramm Mittelstand”) as a cooperation project between a minimum of two companies. Cooperation partner is the company provitro GmbH, located in Berlin.